The documentary investigates the late American Nobel laureate Daniel Carleton Gajdusek's enigmatic discoveries and fall from grace. Gajdusek uncovered prions, the source of mad cow disease, on Papua New Guinea in the fifties, as well as twenty previously unknown tribes and languages. From the late 1940s and onwards he travelled the world, focusing on the most isolated peoples remaining on the globe. He adopted fifty-seven children at his commune at the National Institutes of Health, MA, USA - most of them boys. The film reveals how Gajdusek was in fact a self-proclaimed pedophile, who admitted to having had sex with numerous children.